Asian Journal of Research and Reports in Hepatology

Epithelioid Hemangioendothelioma of the Liver: A Case Report

F. Z. El-Rhaoussi

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

S. M. Daoud *

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

M. Tahiri

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

F. Haddad

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

W. Hliwa

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

A. Bellabah

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

Nisrine Bennani Guebessi

Department of Anatomopathology, CHU Ibn Rochd of Casablanca, Morocco.

Siham Nagib

Department of Anatomopathology, CHU Ibn Rochd of Casablanca, Morocco.

W. Badre

Department of Hepato-Gastroenterology, CHU Ibn Rochd of Casablanca, Morocco.

*Author to whom correspondence should be addressed.

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Abstract

Epithelioid hemangioendothelioma of the liver (EHE) is a rare primary solid tumor of vascular origin [1-4]. EHE represents about 0.4% of all sarcomas and only 20% develop in the liver [5]. It occurs in a non-cirrhotic liver and its pathogenesis remains unknown. The involvement is often multinodular and may mimic metastases of a primary extrahepatic lesion and may delay the diagnosis. The clinical and biological signs are non-specific. Anatomopathological diagnosis can be difficult, requiring the precious help of immunohistochemistry. We report the clinical case of a 22-year-old patient admitted with febrile right hypochondrial pain, peritoneal and pleural effusion syndrome with a severe alteration of general condition. The diagnosis of hepatic EHE was proven on immunohistochemical study of the liver biopsy. The evolution was marked by the death of the patient.

Keywords: Liver, Epithelioid hemangioendothelioma, malignancy, anatomopathological diagnosis

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